Labs and Teams

  • The Anderson research team is focused on linking and integrating large data to understand to drivers of outcomes, costs, and health inequity for children with congenital heart disease.

  • The Pulmonary Hypertension Research Team is committed to investigations that further our understanding of all forms of pulmonary vascular disease.

  • Research in the Chung Lab is focused on the discovery of new genes for human diseases and characterization of the mutation spectrum and molecular mechanism of disease.

  • The Deckelbaum Lab focuses on interactions of cells and lipids, including lipoproteins, model triglyceride-rich emulsions and fatty acids.

    A group of researchers standing for a photo.
  • The Edwards team focuses on children with medical complexity, how critical illness impacts these patients, how they impact pediatric ICUs, and improving their patient- and family-centered outcomes.

  • The Egli Lab studies human development using the earliest cell types, from the fertilized egg to a fully functional and differentiated cell type, such as a beta cell that produces insulin.

  • The Ferrando Laboratory is endeavoring to understand the molecular mechanisms that promote and sustain the malignant proliferation and survival of leukemic cells.

  • The Fujisaki Lab’s current focus is to unveil the clinical significance of IP of the HSPC niche, especially to malignancies.

  • The Gartrell Lab at CUIMC is committed to developing combination immunotherapy regimens for childhood brain cancers and other pediatric solid tumors.

    Multiplex immunofluorescence image of immune infiltrate in a pediatric patient post radiation therapy.
  • The Gershon Lab studies varicella zoster virus (VZV), which causes varicella and herpes zoster.

  • The Gorelik Laboratory at Columbia University is interested in the study of cardiac inflammation and Kawasaki disease. 

    photo of Gorelik lab
  • Research in the Kernie Lab is focused on elucidating mechanisms of the brain’s self-repair following injury.

  • The Lasorella Lab uses the nervous system as a paradigm model to gain molecular and mechanistic insights into the coordination of cell growth and differentiation.

  • Research at the Leibel Lab is focused on the molecular genetics and physiology of weight regulation and diabetes.

  • Research in the Lin Lab is focused on understanding the pathogenesis of acute kidney injury (AKI) and the transition of AKI to chronic kidney disease (CKD).

  • Members of the Lovinsky-Desir Research team focus on understanding and addressing factors in the urban environment that contribute to pediatric asthma.

  • Research in the Mace Lab is focused on understanding the molecular signaling that drives human NK cell development and how this is dysregulated in cases of human disease.

  • The Maegawa Lab focuses on developing therapies for lysosomal storage diseases (LSDs) based on critical pathogenic mechanisms underlying the neurological manifestations of these disorders.

  • The Margolis Lab studies the effects of neurotransmitters and inflammation on enteric nervous system development and function.

  • The Milner Lab researches the genetics and immunopathology of inborn disorders of the immune system, with the goal of identifying pathways relevant for diagnosis and treatment.

  • The Moscona Lab is focused on understanding how enveloped viruses enter cells, and on using this understanding to prevent viral infection.

    image of viral entry
  • The Orange Lab collaborates closely with the Mace Lab to dissect mechanisms of human natural killer (NK) cell maturation and function.

  • The Prince Lab studies the interaction of the host and bacterial pathogens in both the airway and skin.

  • The Sadeghi team works to promote quality, safety, and efficiency in cystic fibrosis clinical research. The aim is to speed the delivery of new and improved therapies to people with cystic fibrosis.

  • The Stockwell team focuses on theory-based translational interventions to promote vaccination among underserved children and adolescents, with an emphasis on health technology and health literacy.

  • Research in the Targoff Lab is focused on the role of nkx genes, cardiac-specific homeodomain transcription factors, in establishing and maintaining cardiomyocyte identity.

  • Members of the Thaker Lab focus on understanding the molecular underpinnings of severe early childhood obesity, and its influence on the clinical manifestations.

  • The Childhood Research in Obesity Prevention (CROP) group studies early-life etiologies and interventions to eliminate racial/ethnic and socioeconomic disparities in obesity and its co-morbidities.

  • Research at the Yamashiro Lab focuses on the preclinical study of novel agents in pediatric solid tumors, in particular neuroblastoma and hepatoblastoma.

  • Our research is focused on the fundamental mechanisms by which cells respond to DNA damage and how these responses impact normal lymphocyte development, lymphomagenesis, and cancer therapy.

  • The two major research interests and goals of the Zhang Lab are epigenetic inheritance and cancer epigenetics.