Yamashiro Lab

Location and Contact Information

Irving Cancer Research Center
1130 St. Nicholas Avenue
ICRC 9-14A
New York, NY 10032
United States

Principal Investigator

Taybandz/Matthews Family Foundation Solid Tumor Laboratory

Research at the Yamashiro Lab focuses on the preclinical study of novel agents in pediatric solid tumors, in particular neuroblastoma and hepatoblastoma. The lab has collaborated with multiple investigators within the Herbert Irving Comprehensive Cancer Center. Currently, the Yamashiro Lab collaborates with:

  1. The Califano Lab on TFAP4 as a master regulator and synthetic lethal interactor of MYCN amplification in neuroblastoma;
  2. Dr. Lloyd Green on therapy of neuroblastoma and brain tumors with a inhibitor of ATF5;
  3. Drs. Eileen Connolly on high-dose radiation on the tumor microenvironment.

Lab Members

  • Debarshi Banerjee, PhD

    • Associate Research Scientist
  • Shuobo Boboila, PhD

    • Associate Research Scientist
  • Eileen Connolly, MD, PhD

    • Assistant Professor of Radiation Oncology

Select Publications

  • ​Boboila S, Lopez G, Yu J, Banerjee D, Kadenhe-Chiweshe A, Connolly EP, Kandel JJ, Rajbhandari P, Silva JM, Califano A, Yamashiro DJ. Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma. Oncogene. 2018. Epub 2018/06/09.

  • Jani A, Shaikh F, Barton S, Willis C, Banerjee D, Mitchell J, Hernandez SL, Hei T, Kadenhe-Chiweshe A, Yamashiro DJ, Connolly EP. High-Dose, Single-Fraction Irradiation Rapidly Reduces Tumor Vasculature and Perfusion in a Xenograft Model of Neuroblastoma. Int J Radiat Oncol Biol Phys. 2016;94(5):1173-80.

  • Banerjee D, Hernandez SL, Garcia A, Kangsamaksin T, Sbiroli E, Andrews J, Forrester LA, Wei N, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK, Kandel JJ, Yamashiro DJ. Notch suppresses angiogenesis and progression of hepatic metastases. Cancer research. 2015;75(8):1592-602.

  • For a complete list of publications, please visit PubMed.gov