Lin Lab

Location and Contact Information

630 West 168th Street
Physicians and Surgeons Building, PS9-401
New York, NY 10032
United States

Principal Investigator

​ Research in the Lin Lab is focused on understanding the pathogenesis of acute kidney injury (AKI) and the transition of AKI to chronic kidney disease (CKD). We take the approaches of cell and molecular biology, renal pathophysiology, and mouse genetics to understand kidney tubular stress response to ischemic injury and metabolic perturbation. Current projects involve regulation of autophagy by FoxO3 transcription factor in kidney epithelial cells as well as generation of animal models to study the mechanism of CKD development in humans born preterm. Our goal is to identify molecular pathways that could be targeted for future therapy to prevent and treat chronic kidney disease.

Lab Members

  • ​Ling (Linda) Li, MD, PhD

    • Associate Research Scientist
    Headshot of linda li
  • Pamela Good, MD

    • Postdoctoral Research Fellow
    Headshot of Pamela Good.
  • Huimin Kang, MD

    • Postdoctoral Research Fellow
    A portrait of Humin Kang.

Select Publications

  • Li L, Zviti R, Ha C, Wang Z, Hill J, and Lin F. Forkhead box O3 (FoxO3) Regulates Renal Tubular Autophagy Following Urinary Tract Obstruction, J Biol Chem. 2017 Aug 18;292(33):13774-13783

  • Li L, Wang ZV, Hill JA and Lin F. New Autophagy Reporter Mice Reveal Dynamics of Proximal Tubular Autophagy, J Am Soc Nephrol. 2014 Feb; 25 (2):305-15