Sabrina Pia Law, MD

1. �Advanced Cardiac Therapies Improving Outcomes Network (ACTION), Site PI. The ACTION learning network consists of clinicians, researchers, parents, and patients from across a 41 national and 5 international medical institutions.The goal is to improve critical outcomes for children with heart failure by uniting providers and families, sharing data and outcomes transparently, improving education and standardizing best practices.The current focus is on improving outcomes for pediatric ventricular assist device (VAD) patients. This VAD learning network approach allows us to make improvements faster across this collaborative system by the creation of clinical guidelines. The Harmonization, Patient Reported Outcomes and Global Quality Initiative committees meet once each per month per month by phone. An annual live meeting is held in addition to live half day or day long sessions at national meetings.

2. Lead of Pediatric VAD Steering Committee. The goal of the committee is to provide input on the strategic planning and coordination of the Pediatric VAD Program. The committee seeks input from each discipline (Heart Failure/ Transplant, Perfusion, ICU, Floor and ICU Nursing Leadership, Floor and ICU nurses, Hematology as well as CT Surgery) to discuss how to best approach the different aspects of care for patients supported by VAD. Every discipline’s expertise is taken into consideration while incorporating policies, procedures and education. So far the committe has been instrumental in developing Institutional Anticoagulation Guidelines for ventricular assist devices in children, and instructional material and curriculum design used locally, as well as Quality Improvement Protocols for Transplant, Cardiomyopathy and Ventricular Assist Device Program

3. Site PI and Co-investigator for Safety and Benefit of a Novel Anticoagulation Protocol for Berlin EXCOR. Prospective multicenter study to evaluate the adherence, safety and efficacy of a novel anticoagulation protocol for children supported on the Berlin Heart EXCOR. US Food and Drug Administration, Orphan products grant.

4. Cardiology Co-Principal Investigator for PUMPKIN Trial Clinical Site, New York Presbyterian Morgan Stanley Children’s Hospital, New York, NY. The PUMPKIN trial is a randomized, multicenter, trial evaluating the investigational Infant Jarvik 2000 Heart System versus the EXCOR Pediatric device in Pediatric patients with heart failure.

5.�Co-Chair for Task Force 9 titled “Pediatric VAD Program Development” . An International Society for Heart and Lung Transplant (ISHLT) Consensus Document titled “ISHLT Consensus Statement on Management of Pediatric and Congenital Heart Disease Patients with Ventricular Assist Devices”.�Developed by Pediatric Thoracic Transplantation and Heart Failure Council. The aim for this document is to provide recommendations that will assist programs in constructing selection and management protocols that can be efficiently administered

6.�Executive Board member of the International Society for Pediatric Mechanical Cardiopulmonary Support (ISPMCS). The mission of this society is to focus on the current problems associated with pediatric cardiac patients during and after acute or chronic cardiac support. The society brings together as many clinicians, bioengineers, and basic scientists to precisely define current problems and suggest solutions with novel approaches. The society was established for further development of novel treatments and devices for cardiovascular health in pediatric populations at the pediatric heart centers around the world. The goal is to educate more bioengineers, medical students, residents, post-doctoral fellows, and junior faculty members in pediatric cardiovascular research. To ensure that the annual conference (International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion continues to be the leading conference for defining the problems of current mechanical circulatory support systems in pediatric patients and suggesting appropriate solutions for underserved pediatric cardiac patients around the globe