Publications
Select Primary Publications
Margolis KG, Cryan JF, Mayer EA. The Microbiota-Gut-Brain Axis: From Motility to Mood. Gastroenterology. 2021. ahead of print.
Miller J, Cantor A, Zachariah P, Ahn D, Martinez M, Margolis KG. Gastrointestinal Symptoms as a Major Presentation Component of a Novel Multisystem Inflammatory Syndrome in Children That Is Related to Coronavirus Disease 2019: A Single Center Experience of 44 Cases. Gastroenterology. 2020 Oct;159(4):1571-1574.e2. doi: 10.1053/j.gastro.2020.05.079. Epub 2020 Jun 4. PMID: 32505742
Hoffman JM, Margolis KG. Building community in the gut: a role for mucosal serotonin. Nat Rev Gastroenterol Hepatol. 2020 Jan;17(1):6-8. doi: 10.1038/s41575-019-0227-6. PMID: 31624372
Margolis KG, Buie TM, Turner JB, Silberman AE, Feldman JF, Murray KF, McSwiggan-Hardin M, Levy J, Bauman ML, Veenstra-VanderWeele J, Whitaker AH, Winter HS. Development of a Brief Parent-Report Screen for Common Gastrointestinal Disorders in Autism Spectrum Disorder. J Autism Dev Disord. 2019 Jan;49(1):349-362. doi: 10.1007/s10803-018-3767-7.
Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, Caron MG, Margolis KG. Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression. Gastroenterology. 2019 Aug;157(2):507-521.e4. doi: 10.1053/j.gastro.2019.04.022. Epub 2019 May 7. PMID: 31071306
Margolis KG*, Li ZS, Stevanovic K, Saurman V, Blakely R, Veenstra-Vanderweele J, Israelyan N, and Gershon, MD. Modulation of SERT leads to alterations in Enteric Nervous System Development and Gastrointestinal Functions: Implications in Autism and SSRI Exposure. J Clin Invest. 2016;126(6):2221- 2235.*corresponding author
Margolis KG, Gershon MD and Bogunovic M. Cellular Organization of Neuro-Immune Interactions in the GI Tract. Trends Immunol. (Cell Press) 2016 Jul;37(7):487-501.
Margolis KG, Stevanovic K, Yang Q, Oravecz T, Diacou A, Gershon M. Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine. Gut 2014 Jun;63(6):928-37.
Margolis KG, Stevanovic KD, D’autreaux F, Li ZS, Chalazonitis A, and Gershon MD. Enteric Neuronal Development as a Determinant of Intestinal Inflammation. Gastroenterology. 2011 Aug;141(2):588-598.
D’autreax F & Margolis KG, Morika Y Csejesi P, Ahuja A and Gershon M. Characterization of the Enteric Nervous System in the Hand2 Haploinsufficient Mouse. Gastroenterology 2011 Aug;141(2):576-587.
Select Collaborative Publications
Bhattarai Y, Si J, Pu M, Ross OA, McLean PJ, Till L, Moor W, Grover M, Kandimalla KK, Margolis KG, Farrugia G, Kashyap PC. Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson's disease. Gut Microbes. 2021 Jan 1;13(1):1866974. doi: 10.1080/19490976.2020.1866974. PMID: 33459114
Autism Spectrum Disorder as a Brain-Gut-Microbiome Axis Disorder. Saurman V, Margolis KG, Luna RA.Dig Dis Sci. 2020 Mar;65(3):818-828. doi: 10.1007/s10620-020-06133-5.PMID: 32056091 Free PMC article. Review.
Prenatal Stress and Maternal Immune Dysregulation in Autism Spectrum Disorders: Potential Points for Intervention. Beversdorf DQ, Stevens HE, Margolis KG, Van de Water J.Curr Pharm Des. 2019;25(41):4331-4343. doi: 10.2174/1381612825666191119093335.PMID: 31742491 Free PMC article. Review.
Paul Andrew Muller, Balázs Koscsó, Gaurav Manohar Rajani, Korey Stevanovic, Marie-Luise Berres, Daigo Hashimoto, Arthur Mortha, Xiu-Min Li, Daniel Mucida, E. Stephanie Dahan, Kara Gross Margolis, Michael Gershon, Miriam Merad, Milena Bogunovic. Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility. Cell 2014; 158(2):300-13.
Gross ER, Gershon MD, Margolis KG, Gertsberg ZV, Cowles RA. Neuronal Serotonin Regulates Growth of the Intestinal Mucosa in Mice. Gastroenterology 2012 Aug;143(2):408-1.
Li Z, Chalazonitis A, Huang YY, Mann JJ, Margolis KG, Yang QM, Kim DO, Côté F, Mallet J, Gershon MD. Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/ survival of enteric dopaminergic neurons. J Neuroscience 2011 Jun 15;31(24):8998-9009.