Compassionate, Expert Care for Children and Adolescents With Hormone Disorders
Endocrinology, Diabetes, and Metabolism
Members of the Division of Endocrinology, Diabetes, and Metabolism conduct over 8,000 patient visits annually, providing comprehensive care for infants to young adults with issues including congenital adrenal hyperplasia, obesity, diabetes, and disorders of the thyroid, growth, puberty, bone, and pituitary gland. Through our clinical programs, we:
- Provide endocrine care to obese adolescents who are considering or have undergone bariatric surgery at Columbia’s Adolescent Bariatric Surgery Program
- Evaluate and treat children with bone disease through our pediatric bone mineral density service
- Provide state-of-the-art care with nationally leading outcomes to children and adolescents with diabetes mellitus (DM) at The Naomi Berrie Diabetes Center. The center’s five pediatric endocrinologists, devoted specifically to DM, offer an insulin pump program and educational programs for children with DM, their families, and caregivers
- Screen newborns as a designated site for the NYS Congenital Adrenal Hyperplasia (CAH) and Newborn Thyroid Screening programs
Promotions
- Patricia Vuguin, MD
- Professor of Pediatrics at CUMC
- Jee-Young (Nina) Ham, MD
- Associate Professor of Pediatrics at CUMC
Honors
- Ileana Vargas, Ilene Fennoy, Abeer Hassoun, Kristen Williams, Michael Novogroder, and Sharon Oberfield were listed on the 2023 Top Doctors List in NY Magazine.
- Sharon Oberfield, MD, was recognized in the New York Times Super Doctors 2023 list.
- Ilene Fennoy, MD, was quoted in the New York Times: “New Drugs Can Fix Teenage Obesity, but Young People Don’t Get Them”
Retirement
- Barney Softness, MD
- Recently transitioned to the role of Special Lecturer
Major Grants
- National Institutes of Health (NIH) T-32 training grant (19th consecutive year).
- Agouti-related Peptide (AgRP) and the GH/IGF-1 Axis in Children. Pfizer. Co-I: Sharon Oberfield, MD
- Dissecting the opposing roles of the Notch1 and Notch2 receptor in NASH. Lawrence R. Stanberry Pediatric Fellows Research Grant. Jonathan Steinman.
- Determinants of zonation of liver inflammation and fibrosis in pediatric NASH. CaMPR-ISP grant. Co-I: Jonathan Steinman, MD, PhD
Selected Publications
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Weiner A, Zhang M, Ren S, Tchang B, Gandica R, Murillo J. Progression from prediabetes to type 2 diabetes mellitus in adolescents: a real world experience. Front Clin Diabetes Healthc. 2023 May 9;4:1181729. doi: 10.3389/fcdhc.2023.1181729. PMID: 37228785; PMCID: PMC10204924.Kwak SH, Sriniva S, Chen L, Todd J, Mercader J, Jensen E, Divers J, Mottl A, Pihoker C, Gandica R, Laffel L, Isganaitis E, Haymond M, Levitsky L, Pollin T, Florez J, Flannick J. Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes. Res Sq. 2023 May 18:rs.3.rs-2886343. doi: 10.21203/rs.3.rs-2886343/v1.
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Burghard AC, Rahming V, Sonnett Fisher A, Zitsman J, Oberfield SE, Fennoy I. The Relationship Between Metabolic Comorbidities and Post-surgical Weight Loss Outcomes in Adolescents Undergoing Laparoscopic Sleeve Gastrectomy. Horm Res Paediatr. 2023 Jun 23. doi: 10.1159/000531655.
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Cousminer D, Bradfield JP, Kember RL, Ulrich A, Balkiyarova Z, Alyass A, Aris IM, Bell JA, Broadaway KA, Chen Z, Chai J, Davies NM, Fernandez-Orth D, Bustamante M, Fore R, Ganguli A, Heiskala A, Hottenga J, Íñiguez C, Kobes S, Leinonen J, Lowry E, Lyytikainen L, Mahajan A, Pitkänen N, Schnurr TM, Have CT, Strachan DP, Thiering E, Vogelezang S, Wade KH, Wang CA, Wong A, Holm LA, Chesi A, Choong C, Cruz M, Elliott P, Franks S, Frithioff-Bøjsøe C, Gauderman WJ, Glessner JT, Gilsanz V, Griesman K, Hanson RL, Kaakinen M, Kalkwarf H, Kelly A, Kindler J, M Kähönen, Lanca C, Lappe J, Lee NR, McCormack S, Mentch FD, Mitchell JA, Mononen N, Niinikoski H, Oken E, Pahkala K, Sim X, Teo Y, Baier LJ, van Beijsterveldt T, Adair LS, Boomsma DI, de Geus E, Guxens M, Eriksson JG, Felix JF, Gilliland FD, Hansen T, Hardy R, Hivert M, Holm J, Jaddoe VWV, Järvelin M, Lehtimäki T, Mackey DA, Meyre D, Mohlke KL, Mykkänen J, Oberfield S, Pennell CE, Perry JRB, Raitakari O, Rivadeneira F, Saw S, Sebert S, Shepherd JA, Standl M, Sørensen TIA, Timpson NJ, Torrent M, Willemsen G, Hypponen E, Power C, McCarthy MI, Freathy RM, Widén E, Hakonarson H, Prokopenko I, Voight BF, Zemel BS, Grant SAF. Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes. Genome Biology. Accepted for publication, 11/30/2023.
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Moran GW, Steinman JB, Tillotson CV, Carpenter CP, Hays T, Ham JN, Li B. Virilization of a 46,XX Fetus Following Aromatase Inhibitor Treatment of Breast Cancer. Pediatrics. 2023 May 2:e2022060568. doi: 10.1542/peds.2022-060568.
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Zhu N, LeDuc CA, Fennoy I, Laferr Re B, Doege CA, Shen Y, Chung WK, Leibel RL. Predicted loss of function alleles in Bassoon (BSN) are associated with obesity. medRxiv [Preprint]. 2023 Feb 23:2023.02.19.23285978. doi: 10.1101/2023.02.19.23285978.
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Bionic Pancreas Research Group (Kristen Williams and Natasha Leibel are members). The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes. Diabetes Care. 2023 Mar. PMID 37000680.
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Salama M, Balagopal B, Fennoy I, Kumar S. Childhood Obesity, Diabetes and Cardiovascular Disease Risk. J Clin Endocrinol Metab. 2023 Jun 16:dgad361. doi: 10.1210/clinem/dgad361.
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Nichols P, Rahming V, Weiner A, Sopher AB. Primary Adrenal Insufficiency Masked by an Eating Disorder Diagnosis in an Adolescent Male. JCEM Case Rep. 2023 Aug 9;1(4):luad095. doi: 10.1210/jcemcr/luad095.
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Zemel BS, Shepherd JA, Grant SFA, Lappe JM, Oberfield SE, Mitchell JA, Winer KK, Kelly A, Kalkwarf HJ. Reference ranges for body composition indices by dual energy X-ray absorptiometry from the Bone Mineral Density in Childhood Study Cohort. Am J Clin Nutr. 2023 Oct;118(4):792-803. doi: 10.1016/j.ajcnut.2023.08.006.
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Miller KM, Bauza C, Kanapka LG, Clements MA, DeSalvo DJ, Hood K, Messer LH, Sherr J, Bergamo K, Criego A, Freiner E, Lyons SK, Monzavi R, Moore W, Prahalad P, Simmons JH, Sulik M, Wadwa RP, Weinstock RS, Willi SM, Williams KM, Laffel LM, and the CITY Study Group. Continuous Glucose Monitoring Provides Durable Glycemic Benefit in Adolescents and Young Adults with Type 1 Diabetes: 12-Month Follow-Up Results. Pediatric Diabetes. 2023, Article ID 6718115. https://doi.org/10.1155/2023/6718115
Highlights
Columbia Children's Health Webinar: Pediatric Obesity: An Expert Review of the New AAP Guidelines
A panel of pediatric specialists from Columbia University and NewYork-Presbyterian Morgan Stanley Children’s Hospital discuss the new AAP guidelines on pediatric obesity.