Publications
Alternative polyadenylation alters protein dosage by switching between intronic and 3′UTR sites. Prisco, N., Ford, C., Elrod, N.D., Lee, W., Tang, L.C., Huang, K.-L., 4,7, Lin, A., Ji, P., Jonnakuti, V.S., Boyle, L., Cabaj, M., Botta, S., Õunap, K., Reinson, K., Wojcik, M.H., Rosenfeld, J.A., Bi, W., Tveten, K., Prescott, T., Gerstner, T., Schroeder, A., Fong, C.-T., George-Abraham, J.K., Buchanan, C.A., Hanson-Khan, A., Bernstein, J.A., Nella, A.A., Chung, W.K., Brandt, V., Jovanovic, M., Targoff, K.L., Yalamanchili, H.K., Wagner, E.J., Gennarino, V.A. Science Advances, 9(7): 4814, 2023. (PMID: 36800428)
Activation of Nkx2.5 Transcriptional Program is Required for Adult Myocardial Repair. * de Sena-Tomás, C., Aleman, A., Ford, C., Varshney, A., Yao, D., Harrington, J., Saúde, L., Ramialison, M., and Targoff, K.L. Nature Communications, 13(1): 2970, 2022. (PMID: 35624100)
Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Morikawa, K., Furuhashi, K., de Sena-Tomas, C., Garcia-Garcia, A., Gallerani, N., Yamamoto, H., Klein, A., Bekdash, R., Park, S-H.E., Collins, G.S., Kawano, F., Sato, M., Lin, C-S., Targoff, K.L., Au, E., Salling, M., Yazawa, M. Nature Communications, 2020; 11(1): 2141. (PMID: 32358538)
Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development. Budine, T.E., de Sena-Tomas, C., Williams, M.L.K., Sepich, D.S., Targoff, K.L., Solnica-Krezel, L. Developmental Biology, 462(2): 223-234, 2020. (PMID: 32272116)
Real-time Volumetric Microscopy of in-vivo Dynamics and Large-Scale Samples with SCAPE 2.0. Voleti, V., Li, W., Patel K.B., Campos, C.P., Bharadwaj, S., Ford, C., Chentao, W., Kotaro, K., Caspar, M., Targoff, K.L., Hillman, E.M.C. Nature Methods, 14: 1054-1062, 2019. (PMID: 31562489)
Optical Imaging of Metabolic Dynamics in Animals. Shi, L., Zheng, C., Shen, Y., Chen, Z., Silveira, E., Zhang, L., Wei, M., Liu, C., de Sena-Tomas, C., Targoff, K.L., Min, W. Nature Communications, August 6th, 2018; 9(1): 2995. (PMID: 30082908)
nkx Genes Establish SHF Cardiomyocyte Progenitors at the Arterial Pole and Pattern the Venous Pole through Isl1 Repression. Colombo, S., de Sena-Tomás, C., George, V., Werdich, A.A., Kapur, S., MacRae, C.A., and Targoff, K.L. Development, February 5th, 2018; 145(3).
(PMID: 29361575)
nkx2.5 is Essential to Establish Normal Heart Rate Variability in the Zebrafish Embryo. Harrington, J.K., Sorabella, R., Tercek, A., Isler, J.R., Targoff, K.L.* Am J Physiol Regulatory Integrative Comparative Physiology, June 14th, 2017. (PMID: 28615160)
FGF Signaling Enforces Cardiac Chamber Identity in the Developing Ventricle. Pradhan, A., Zeng, X.X., Sidhwani, P., Marques, S. George, V., Targoff, K.L., Chi, N., Yelon, D. Development, April 1st, 2017; 144(7): 1328-1338. (PMID: 28232600)
nkx2.5 Regulates Endothelin Converting Enzyme-1 During Pharyngeal Arch Patterning. Iklé, J.M., Tavares, A.L., King, M., Ding, H., Colombo, S., Firulli, B.A., Firulli, A.B., Targoff K.L., Yelon, D., Clouthier, D.E. Genesis, Jan. 20th, 2017. (PMID: 28109039)n
Origin, Specification, and Plasticity of the Great Vessels of the Heart. Nagelberg, D., Wang, J., Su, R., Torres-Vázquez, J., Targoff, K.L., Poss, K.D., Knaut, H. Current Biology, 25(16): 2099-110, 2015. (PMID: 26255850)
An Early Requirement for nkx2.5 Ensures the First and Second Heart Field Ventricular Identity and Cardiac Function into Adulthood. George, V., Colombo, S., Targoff, K.L.* Developmental Biology, 400(1): 10-22, 2015. (PMID: 25536398)
Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling. Wei, L., Shen, Y., Xu, F., Hu, F., Harrington, J.K., Targoff, K.L., Min, W. ACS Chemical Biology, 10(3): 901-8, 2015. (PMID: 25560305)
nkx Genes are Essential for Maintenance of Ventricular Identity. Targoff, K.L., Colombo, S., George, V., Schell, T., Kim, S.-H., Solnica-Krezel, L., Yelon, D. Development, 140(20): 4203-13, 2013. (PMID: 24026123)
UV Microspot Irradiator at Columbia University. Bigelow, A.W., Ponnaiya, B., Targoff, K.L., Brenner, D. Radiation and Environmental Biophysics, 52(3): 411-7, 2013. (PMID: 23708525)
nkx Genes Regulate Heart Tube Extension in Zebrafish and Exert Differential Effects on Ventricular and Atrial Cell Number. Targoff, K.L., Schell, T., Yelon, D. Developmental Biology, 322(2): 314-321, 2008. (PMID: 18718462)