Clinical Trials

  • Principal Investigator:

    Rakesh Sahni, MD
    The purpose of this study is to see if the use of bubble nasal continuous positive airway pressure (NCPAP) at a pressure of 6-7 centimeters of water (cm H2O) in very low birth weight (VLBW) infants is associated with improved gas exchange without any related changes in vital signs.
  • Principal Investigator:

    Stephanie Levasseur, MD
    Although supraventricular tachycardia (SVT), including atrial flutter (AF), are the most common causes of intended in-utero fetal therapy, none of the medication used to date has been evaluated for their effects on the mother and her baby in a randomized controlled clinical trial (RCT). In the absence of such evidence, there is no consensus for the optimal management. The purpose of the FAST Research study is to improve the care of pregnancies affected by AF or SVT. The aim of the FAST Registry is to record the treatment your doctor prescribes, your ongoing care, and the outcome of your...
  • Principal Investigator:

    Stephanie Levasseur, MD
    The purpose of the study is to clarify the best treatment for your babys condition by looking at how well the medicine worked to bring your babys heart rate back to normal and if you experienced any side-effects from the treatment. You are being asked to take part in a research study because your fetus has been diagnosed with a fast heart rate. Although supraventricular tachycardia (SVT), including atrial flutter (AF), are the most common causes of intended in-utero fetal therapy, none of the medication used to date has been evaluated for their effects on the mother and her baby in a...
  • Principal Investigator:

    Wendy Kay Chung, MD
    This study is designed to determine the role of specific genes in obesity and/or type 2 diabetes mellitus. Patients who are severely obese, and/or with an onset of type 2 diabetes at less than 25 years of age. Ideally, we would like to have families involved in this study. The ideal family is one in which NOT everyone in the family is obese or diabetic. Families in which one or neither parent is obese/diabetic, and some but not all children are obese/diabetic, are ideal.
  • Principal Investigator:

    Wendy Kay Chung, MD
    The goal of this study is to better understand the genetic causes of weight gain. Your participation will help us understand how why some people gain more weight and why others do not.We will ask you questions about your weight and your height to determine if you are eligible. If you are eligible, we will invite you to participate. To participate, we will ask you questions about your medical history and eating habits and ask you to provide a blood or saliva sample for genetic testing. We will test the DNA from your blood or saliva sample to try to identify if you have a genetic cause for your...
  • Principal Investigator:

    Vidhu Thaker, MD
    We will enroll children with severe early onset obesity (BMI - 99th percentile) diagnosed prior to 6 years of age. We will ask questions about their health, eating behavior and perform a brief physical examination. We will collect saliva or blood to perform genetic testing. We will also invite family members to participate in the genetic study.
  • Principal Investigator:

    Cindy Elizabeth Neunert, MD
    The purpose of this study is investigate the safety and effectiveness of eltrombopag (investigational drug) in treating children and adolescents with newly-diagnosed immune thrombocytopenia (ITP), which is a rare blood disorder.
  • Principal Investigator:

    Vidhu Thaker, MD
    We are interested in studying the health of you and your family. Our study involves completing an online survey about your and your family's health and behaviors, and giving us access to basic health information that includes you and your child's vitals, weight/height, and BMI. You can receive up to $25 in Amazon pay cards for your participation. Spanish/English speakers who have a child 5 - 12 years of age are eligible to participate.
  • Principal Investigator:

    Alice Lee, MD
    The purpose of this study is to find the best dose of Palbociclib that can be given safely with chemotherapy in children and young adults with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) which has come back or has not responded to standard therapy. Palbociclib is considered experimental because it has not been approved by the United States (US) Food and Drug Administration (FDA) for treating children with Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LL). Palbociclib works by targeting proteins that are necessary for cell growth. Palbociclib is given by...
  • Principal Investigator:

    Ilene Fennoy, MD
    We are doing this research study to find out about what happens to children who are overweight and how the things we recommend as a part of routine clinical care affect your child. The purpose of this study is to understand what happens to children as a result of being overweight, to link these outcomes to specific clinical measures and to determine how treatment affects the physical and clinical features of overweight or obesity. To achieve this aim we want to formalize our ongoing clinical chart review into a database for our patients.

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