Clinical Trials

  • Principal Investigator:

    Nobuko Hijiya, MD
    This study is called a screening study and the purpose of this study to find better ways to diagnose and treat leukemia that has come back after treatment or difficult to treat. Bone marrow, blood, and medical information about cancer and treatment will be collected. The results from this screening study may give other information about leukemia that is important when deciding how to best treat leukemia.
  • Principal Investigator:

    Rudolph L. Leibel, MD
    The Physiology of the Weight Reduced State (POWERS) is a national research study designed to discover and learn what happens to the human body after weight loss and to learn why some people regain their lost weight. Understanding why this happens could help health professionals improve strategies for successful weight loss maintenance after weight loss. POWERS is a research study with a goal to understand the changes in the body that occur after weight loss and learn how these changes affect the ability to keep the weight off. It involves universities, medical centers, researchers, and most...
  • Principal Investigator:

    Ilene Fennoy, MD
    We are doing this research study to find out what happens to children who are overweight and how the things we recommend as a part of routine clinical care affect your child. The purpose of this study is to understand what happens to children as a result of being overweight, to link these outcomes to specific clinical measures, and to determine how treatment affects the physical and clinical features of overweight or obesity. To achieve this aim we want to formalize our ongoing clinical chart review into a database for our patients.
  • Principal Investigator:

    Steven J. Lobritto, MD
    The purpose of this study is to find out if a new laboratory blood test for patients with Wilson's disease can accurately and reliably measure so-called free copper, also known as non-ceruloplasmin copper (NCC). Participation will last about 12 months. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).
  • Principal Investigator:

    Melissa S. Stockwell, MD, MPH
    We are doing this study to understand how COVID, the infection caused by a virus called SARS-CoV-2 affects the body, and why some people who got COVID are still sick many months after being infected. Help us to better understand the long-term effects of COVID. If you or your child has had COVID or is feeling the long-term effects of COVID, you might be able to help us understand more about it and treat it. We are seeking volunteers who are under 25 to join the NIH RECOVER initiative. Once someone is enrolled, they will fill out a survey for us and take a home blood test, they will then in 6...
  • Principal Investigator:

    Steven J. Lobritto, MD
    In this research, we want to learn more about how to improve care for children who are listed for or who have received a liver transplant. The goal of this research is to look at how different hospitals treat these children and to look at their outcomes to help improve care, decrease complications, shorten length of hospital stay, reduce hospital re-admissions and to possibly lower mortality rates and decrease adverse events, such as organ rejection, infection, and bleeding. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).
  • Principal Investigator:

    Steven J. Lobritto, MD
    The purpose of the study is to collect scientific data on pediatric liver transplantation to learn more about how children do after liver transplant. Collecting these data is expected to help researchers learn more about liver transplant in children. This information may improve medical care of your child and other children who need and who have received liver transplants. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).
  • Principal Investigator:

    Steven J. Lobritto, MD
    The purpose of the study is to collect scientific data on pediatric liver transplantation to learn more about how children do after liver transplant. Collecting these data is expected to help researchers learn more about liver transplant in children. This information may improve medical care of your child and other children who need and who have received liver transplants. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).
  • Principal Investigator:

    Nobuko Hijiya, MD
    The purpose of this study is to find the best dose of Palbociclib that can be given safely with chemotherapy in children with solid tumor which has come back or has not responded to the standard therapy. Palbociclib works by targeting proteins that are necessary for cell growth. Palbociclib will be given by mouth on Days 1-14 of a 21-day cycle. It will be given in combination with chemotherapy drugs Irinotecan and Temozolomide.
  • Principal Investigator:

    Nobuko Hijiya, MD
    This study will utilize an investigational drug combination (also known as the study drugs) called relatlimab and nivolumab as a possible treatment for recurrent/relapsed (returned) or refractory (treatment-resistant) cHL and NHL. An investigational drug combination is one that has not been approved by regulatory agencies, such as the United States (US) Food and Drug Administration (FDA), European Union (EU) European Medicines Agency (EMA), or others. The purpose of this study is to learn about the safety and effectiveness of nivolumab and relatlimab in participants with recurrent/relapsed or...

Pages